PTHR43156

Bacterial Sigma Factor Regulator
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short nameBact_Sigma-Reg
AI

Description

AI-generatedUnreviewed
The protein family described is involved in regulatory processes related to stress response and sporulation in bacteria. Members of the family function as regulators of sigma factors, which are proteins that control the transcription of specific sets of genes. They exhibit phosphatase activity, often dephosphorylating specific proteins to activate sigma factors in response to environmental or energy stress. Some members also have kinase activity and can phosphorylate other proteins, playing a role in signal transduction pathways. The family includes proteins that participate in the cross-regulation of carbon and glucose metabolisms, as well as proteins that act as independent regulators sensitive to osmosensory signals. They are characterized by the presence of domains such as PAS, which may sense cellular energy levels, and anti-sigma factor domains, which are involved in the regulation of sigma factor activity.
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.