PTHR43523

GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE-RELATED

PANTHER entry
Member databasePANTHER
PANTHER typefamily

Description
Imported from IPR011831

This enzyme, glucose-1-phosphate adenylyltransferase, is also called ADP-glucose pyrophosphorylase. The plant form is an alpha2, beta2 heterodimer, allosterically regulated in plants
[2]
. Both subunits are homologous and included in this entry. In bacteria, both homomeric forms of GlgC and more active heterodimers of GlgC and GlgD have been described
[1]
. This entry describes the GlgC subunit only. This enzyme appears in variants of glycogen synthesis pathways that use ADP-glucose, rather than UDP-glucose as in animals.

References
Imported from IPR011831

1.The ADP-glucose pyrophosphorylase from Streptococcus mutans provides evidence for the regulation of polysaccharide biosynthesis in Firmicutes. Asencion Diez MD, Demonte AM, Guerrero SA, Ballicora MA, Iglesias AA. Mol. Microbiol. 90, 1011-27, (2013). View articlePMID: 24112771

2.Crystal structure of potato tuber ADP-glucose pyrophosphorylase. Jin X, Ballicora MA, Preiss J, Geiger JH. EMBO J. 24, 694-704, (2005). View articlePMID: 15692569

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