This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member database | PANTHER |
PANTHER type | family |
Short name | UPF0173_UPF0282_UlaG_hydrolase AI |
Description
AI-generatedUnreviewed
The UPF0173/UPF0282/UlaG protein family includes metal-dependent hydrolases and probable L-ascorbate-6-phosphate lactonases. Members of the UPF0173 and UPF0282 families are characterized by their metal-dependent hydrolase activity, although specific substrates and biological roles are not well-defined. Proteins belonging to the UlaG family are implicated in the utilization of L-ascorbate under anaerobic conditions, catalyzing the hydrolysis of L-ascorbate-6-phosphate into 3-keto-L-gulonate-6-phosphate. This activity is essential for L-ascorbate metabolism, highlighting the family's role in bacterial vitamin C utilization pathways. The diverse functions within this family reflect a range of enzymatic activities linked to metal ion coordination and hydrolysis, with implications for various metabolic processes.
Integrated to
External Links
Representative structure
3x30: Crystal structure of metallo-beta-lactamase from Thermotoga maritima