This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member database | PANTHER |
PANTHER type | family |
Short name | Zinc_ADH AI |
Description
AI-generatedUnreviewed
The zinc-containing alcohol dehydrogenase family is a group of enzymes that catalyze the oxidation of alcohols to aldehydes or ketones, and the reduction of aldehydes or ketones to alcohols, using NAD(+) or NADH as coenzymes. Members of this family exhibit a broad substrate specificity, including primary and secondary alcohols, and are involved in various metabolic processes such as ethanol catabolism, retinoid metabolism, fatty acid omega-oxidation, and formaldehyde detoxification. They play crucial roles in physiological processes like hypoxic survival, pheromone biosynthesis, and cellular response to toxic metabolites. The family includes several classes and subfamilies, each with distinct substrate preferences and functions, ranging from the metabolism of ethanol and long-chain fatty acids to the biosynthesis of plant secondary metabolites and pheromones.