PTHR45933

PROTEIN C2-DOMAIN ABA-RELATED 4

PANTHER entry
Member databasePANTHER
PANTHER typefamily

Description
Imported from IPR044562

This entry includes C2-domain abscisic acid-related protein CAR1-11 from Arabidopsis and GTPase activating protein 1 (OsGAP1) from rice. CARs interact with the PYR/PYL ABA receptors and recruit them to membranes in a Ca2+-dependent manner
[1]
. OsGAP1 is a soluble protein that can loosely associate with plasma membrane. It can also interact with an unconventional G-protein, OsYchF1, and stimulate its NTPase activities
[2]
.

References
Imported from IPR044562

1.C2-domain abscisic acid-related proteins mediate the interaction of PYR/PYL/RCAR abscisic acid receptors with the plasma membrane and regulate abscisic acid sensitivity in Arabidopsis. Rodriguez L, Gonzalez-Guzman M, Diaz M, Rodrigues A, Izquierdo-Garcia AC, Peirats-Llobet M, Fernandez MA, Antoni R, Fernandez D, Marquez JA, Mulet JM, Albert A, Rodriguez PL. Plant Cell 26, 4802-20, (2014). PMID: 25465408

2.Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1). Yung YL, Cheung MY, Miao R, Fong YH, Li KP, Yu MH, Chye ML, Wong KB, Lam HM. J Biol Chem 290, 23984-96, (2015). PMID: 26286751

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