PTHR45998

Serine/threonine-specific protein kinases
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short nameSer/Thr-specific_kinases
AI

Description

AI-generatedUnreviewed
This family of proteins includes serine/threonine kinases that are involved in a variety of cellular processes. Members are known to phosphorylate substrates on serine and threonine residues, which is a key mechanism in regulating intracellular signaling pathways. Some proteins in this family have been shown to autophosphorylate and may also have the capacity to phosphorylate on tyrosine residues, although this activity towards other proteins is not clearly established. Functions attributed to these kinases include roles in secretory vesicle trafficking, ductal morphogenesis in the mammary gland, TGF-beta signaling, and vacuolar processing and morphology. The diverse functions suggest that these kinases are involved in both intracellular signaling and the regulation of cellular structures.
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