PTHR47248

BPTI/Kunitz domain-containing protein
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short nameBPTI/Kunitz_domain
AI

Description

AI-generatedUnreviewed
This family of proteins includes inhibitors that possess a BPTI/Kunitz domain, which is known for its role in protease inhibition. Members of this family are involved in various biological processes, including the regulation of proteolytic pathways, such as those involved in blood coagulation, fibrinolysis, and inflammation. The domain's inhibitory activity is typically directed against serine proteases, and it functions by binding to the active site of the target protease, thereby preventing substrate access and catalysis. The presence of this domain in allergens like Ani s 1 suggests a role in immune response, where it may protect the allergen from degradation or modulate host immune functions. The diversity of proteins containing the BPTI/Kunitz domain reflects the versatility and importance of this inhibitory mechanism in various physiological contexts.
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