This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member database | PANTHER |
PANTHER type | family |
Short name | SMP-30/CGR1_Lactonase AI |
Description
AI-generatedUnreviewed
The SMP-30/CGR1 family proteins are characterized by their lactonase activity, which plays a role in maintaining membrane homeostasis, particularly in cells with compromised membrane integrity. Some family members are known to contribute to bacitracin resistance and may act on various lactones, although their natural substrates remain unidentified. Additionally, certain proteins within this family can degrade organophosphorus compounds, including nerve agents, suggesting a broader substrate specificity. The activity of these enzymes is sensitive to chelating agents, indicating a possible dependence on metal ions for their lactonase function.