PF00029

Connexin

Pfam entry
Member databasePfam
Pfam typedomain
Short nameConnexin
ClanTransporter
Author Sonnhammer ELL;0000-0002-9015-5588
Sequence Ontology0000417

Description

Connexin proteins form gap-junctions between cells. They carry four transmembrane regions, hence why this family now includes Connexin_CCC, which represented the second pair of TMs.

References

1. Sequence and phylogenetic analyses of 4 TMS junctional proteins of animals: connexins, innexins, claudins and occludins. Hua VB, Chang AB, Tchieu JH, Kumar NM, Nielsen PA, Saier MH Jr. J Membr Biol 194, 59-76, (2003). View articlePMID: 14502443

Wikipedia

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