PF00050

Kazal-type serine protease inhibitor domain

Pfam entry
Member databasePfam
Pfam typedomain
Short nameKazal_1
ClanKazal
Author Eddy SR;0000-0001-6676-4706
Sequence Ontology0000417

Description

Usually indicative of serine protease inhibitors. However, kazal-like domains are also seen in the extracellular part of agrins, which are not known to be protease inhibitors. Kazal domains often occur in tandem arrays. Small alpha+beta fold containing three disulphides. Alignment also includes a single domain from transporters in the OATP/PGT family Swiss:P46721.

Wikipedia

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