PF01142

tRNA pseudouridine synthase D (TruD)

Pfam entry
Member databasePfam
Pfam typefamily
Short nameTruD
ClanPseudoU_synth
Author Finn RD;0000-0001-8626-2148 Bateman A;0000-0002-6982-4660 Moxon SJ;0000-0003-4644-1816
Sequence Ontology0100021

Description

TruD is responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs
[2]
. The structure of TruD reveals an overall V-shaped molecule which contains an RNA-binding cleft
[1]
.

References

1.X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold. Ericsson UB, Nordlund P, Hallberg BM. FEBS Lett. 565, 59-64, (2004). View articlePMID: 15135053

2.A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya. Kaya Y, Ofengand J. RNA 9, 711-21, (2003). View articlePMID: 12756329

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