Member database | Pfam |
Pfam type | family |
Short name | RNA_pol_Rpb6 |
Author | Finn RD;0000-0001-8626-2148 |
Sequence Ontology | 0100021 |
Description
Rpb6 is an essential subunit in the eukaryotic polymerases Pol I, II and III. This family also contains the bacterial equivalent to Rpb6, the omega subunit. Rpb6 and omega are structurally conserved and both function in polymerase assembly
[1].
References
1.Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly. Minakhin L, Bhagat S, Brunning A, Campbell EA, Darst SA, Ebright RH, Severinov K. Proc. Natl. Acad. Sci. U.S.A. 98, 892-7, (2001). View articlePMID: 11158566
Further reading
2. The evolving story of the omega subunit of bacterial RNA polymerase. Mathew R, Chatterji D. Trends Microbiol 14, 450-5, (2006). View articlePMID: 16908155