PF01790

Prolipoprotein diacylglyceryl transferase

Pfam entry
Member databasePfam
Pfam typefamily
Short nameLGT
Author Bateman A;0000-0002-6982-4660
Sequence Ontology0100021

Description
Imported from IPR001640

Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase lgt
[1]
is an integral membrane enzyme that catalyses the first reaction of the three-step post-translational lipid modification
[2]
. It transfers the n-acyl diglyceride group onto what will become the N-terminal cysteine of membrane lipoproteins. This enzyme is an integral membrane protein.

References
Imported from IPR001640

1.Lipid modification of bacterial prolipoprotein. Transfer of diacylglyceryl moiety from phosphatidylglycerol. Sankaran K, Wu HC. J. Biol. Chem. 269, 19701-6, (1994). View articlePMID: 8051048

2.Crystal structure of E. coli lipoprotein diacylglyceryl transferase. Mao G, Zhao Y, Kang X, Li Z, Zhang Y, Wang X, Sun F, Sankaran K, Zhang XC. Nat Commun 7, 10198, (2016). View articlePMID: 26729647

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