Member database | Pfam |
Pfam type | conserved site |
Short name | GPS |
Clan | Gain |
Author | Bateman A;0000-0002-6982-4660 |
Sequence Ontology | 0001067 |
Description
References
1.Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif. Krasnoperov V, Lu Y, Buryanovsky L, Neubert TA, Ichtchenko K, Petrenko AG. J Biol Chem 277, 46518-26, (2002). PMID: 12270923
2.Characterization of cis-autoproteolysis of polycystin-1, the product of human polycystic kidney disease 1 gene. Wei W, Hackmann K, Xu H, Germino G, Qian F. J. Biol. Chem. 282, 21729-37, (2007). View articlePMID: 17525154
3.A latrophilin/CL-1-like GPS domain in polycystin-1. Ponting CP, Hofmann K, Bork P. Curr. Biol. 9, R585-8, (1999). View articlePMID: 10469603
4.Structural requirements for alpha-latrotoxin binding and alpha-latrotoxin-stimulated secretion. A study with calcium-independent receptor of alpha-latrotoxin (CIRL) deletion mutants. Krasnoperov V, Bittner MA, Holz RW, Chepurny O, Petrenko AG. J. Biol. Chem. 274, 3590-6, (1999). View articlePMID: 9920906
5.A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. Arac D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Sudhof TC, Brunger AT. EMBO J. 31, 1364-78, (2012). View articlePMID: 22333914
6.alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis. Sugita S, Ichtchenko K, Khvotchev M, Sudhof TC. J. Biol. Chem. 273, 32715-24, (1998). View articlePMID: 9830014