PF02186

TFIIE beta subunit core domain

Pfam entry
Member databasePfam
Pfam typedomain
Short nameTFIIE_beta
ClanHTH
Author Bateman A;0000-0002-6982-4660
Sequence Ontology0000417

Description

General transcription factor TFIIE consists of two subunits, TFIIE alpha Pfam:PF02002 and TFIIE beta. TFIIE beta has been found to bind to the region where the promoter starts to open to be single-stranded upon transcription initiation by RNA polymerase II. The structure of the DNA binding core region has been solved
[1]
and has a winged helix fold.

References

1.Structure of the central core domain of TFIIEbeta with a novel double-stranded DNA-binding surface. Okuda M, Watanabe Y, Okamura H, Hanaoka F, Ohkuma Y, Nishimura Y. EMBO J. 19, 1346-56, (2000). View articlePMID: 10716934

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.