PF02275

Linear amide C-N hydrolases, choloylglycine hydrolase family

Pfam entry
Member databasePfam
Pfam typedomain
Short nameCBAH
ClanNTN
Author Mian N;0000-0003-4284-4749 Bateman A;0000-0002-6982-4660 Griffiths-Jones SR;0000-0001-6043-807X
Sequence Ontology0000417

Description

This family includes several hydrolases which cleave carbon-nitrogen bonds, other than peptide bonds, in linear amides. These include choloylglycine hydrolase (conjugated bile acid hydrolase, CBAH) EC:3.5.1.24, penicillin acylase EC:3.5.1.11 and acid ceramidase EC:3.5.1.23. This domain forms the alpha-subunit for members from vertebral species, see family NAAA-beta, Pfam:PF15508.

References

1. Cloning and characterization of a conjugated bile acid hydrolase gene from Clostridium perfringens. Coleman JP, Hudson LL. Appl. Environ. Microbiol. 61, 2514-20, (1995). View articlePMID: 7618863

Wikipedia

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