PF02302

PTS system, Lactose/Cellobiose specific IIB subunit

Pfam entry
Member databasePfam
Pfam typedomain
Short namePTS_IIB
ClanPhosphatase
Author Mian N;0000-0003-4284-4749 Bateman A;0000-0002-6982-4660
Sequence Ontology0000417

Description

The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The lactose/cellobiose-specific family are one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes. The fold of IIB cellobiose shows similar structure to mammalian tyrosine phosphatases. This family also contains the fructose specific IIB subunit.

References

1. The NMR side-chain assignments and solution structure of enzyme IIBcellobiose of the phosphoenolpyruvate-dependent phosphotransferase system of Escherichia coli. Ab E, Schuurman-Wolters G, Reizer J, Saier MH, Dijkstra K, Scheek RM, Robillard GT. Protein Sci. 6, 304-14, (1997). View articlePMID: 9041631

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