PF02575

YbaB/EbfC DNA-binding family

Pfam entry
Member databasePfam
Pfam typefamily
Short nameYbaB_DNA_bd
ClanYbaB
Author Mian N;0000-0003-4284-4749 Bateman A;0000-0002-6982-4660 Eberhardt R;0000-0001-6152-1369
Sequence Ontology0100021

Description

This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure [1-3]. The conformation of the DNA is changed when bound to these proteins
[1]
. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage
[2]
.

References

1.Borrelia burgdorferi EbfC defines a newly-identified, widespread family of bacterial DNA-binding proteins. Riley SP, Bykowski T, Cooley AE, Burns LH, Babb K, Brissette CA, Bowman A, Rotondi M, Miller MC, DeMoll E, Lim K, Fried MG, Stevenson B. Nucleic Acids Res. 37, 1973-83, (2009). View articlePMID: 19208644

2.Crystal structure of YbaB from Haemophilus influenzae (HI0442), a protein of unknown function coexpressed with the recombinational DNA repair protein RecR. Lim K, Tempczyk A, Parsons JF, Bonander N, Toedt J, Kelman Z, Howard A, Eisenstein E, Herzberg O. Proteins 50, 375-9, (2003). View articlePMID: 12486730

Further reading

3. DNA-binding by Haemophilus influenzae and Escherichia coli YbaB, members of a widely-distributed bacterial protein family. Cooley AE, Riley SP, Kral K, Miller MC, DeMoll E, Fried MG, Stevenson B. BMC Microbiol. 9, 137, (2009). View articlePMID: 19594923

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.