Member database | Pfam |
Pfam type | family |
Short name | HIN |
Clan | OB |
Author | Bateman A;0000-0002-6982-4660 |
Sequence Ontology | 0100021 |
Description
References
1.Structural basis for termination of AIM2-mediated signaling by p202. Ru H, Ni X, Zhao L, Crowley C, Ding W, Hung LW, Shaw N, Cheng G, Liu ZJ. Cell Res 23, 855-8, (2013). PMID: 23567559
2.Structural mechanism of DNA recognition by the p204 HIN domain. Fan X, Jiang J, Zhao D, Chen F, Ma H, Smith P, Unterholzner L, Xiao TS, Jin T. Nucleic Acids Res 49, 2959-2972, (2021). PMID: 33619523
3.Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. Jin T, Perry A, Jiang J, Smith P, Curry JA, Unterholzner L, Jiang Z, Horvath G, Rathinam VA, Johnstone RW, Hornung V, Latz E, Bowie AG, Fitzgerald KA, Xiao TS. Immunity 36, 561-71, (2012). View articlePMID: 22483801
Integrated to
Representative structure
4lnq: Crystal structure of Ifi202 HINa domain in complex with 20bp dsDNA