PF02778

tRNA intron endonuclease, N-terminal domain

Pfam entry
Member databasePfam
Pfam typedomain
Short nametRNA_int_endo_N
ClantRNA-IECD_N
Author Enright A;0000-0002-6090-3100 Ouzounis C;0000-0002-0086-8657 Bateman A;0000-0002-6982-4660 Griffiths-Jones SR;0000-0001-6043-807X
Sequence Ontology0000417

Description

Members of this family cleave pre tRNA at the 5' and 3' splice sites to release the intron EC:3.1.27.9.

References

1. Properties of H. volcanii tRNA intron endonuclease reveal a relationship between the archaeal and eucaryal tRNA intron processing systems. Kleman-Leyer K, Armbruster DW, Daniels CJ. Cell 89, 839-47, (1997). View articlePMID: 9200602

2. Crystal structure and evolution of a transfer RNA splicing enzyme. Li H, Trotta CR, Abelson J. Science 280, 279-84, (1998). View articlePMID: 9535656

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