PF03629

Carbohydrate esterase, sialic acid-specific acetylesterase

Pfam entry
Member databasePfam
Pfam typedomain
Short nameSASA
ClanSGNH_hydrolase
Author Finn RD;0000-0001-8626-2148
Sequence Ontology0000417

Description

The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665
[1, 2]
.

References

1.The structure at 1.6 Angstroms resolution of the protein product of the At4g34215 gene from Arabidopsis thaliana. Bitto E, Bingman CA, McCoy JG, Allard ST, Wesenberg GE, Phillips GN Jr. Acta Crystallogr. D Biol. Crystallogr. 61, 1655-61, (2005). View articlePMID: 16301800

2.Functionally defective germline variants of sialic acid acetylesterase in autoimmunity. Surolia I, Pirnie SP, Chellappa V, Taylor KN, Cariappa A, Moya J, Liu H, Bell DW, Driscoll DR, Diederichs S, Haider K, Netravali I, Le S, Elia R, Dow E, Lee A, Freudenberg J, De Jager PL, Chretien Y, Varki A, MacDonald ME, Gillis T, Behrens TW, Bloch D, Collier D, Korzenik J, Podolsky DK, Hafler D, Murali M, Sands B, Stone JH, Gregersen PK, Pillai S. Nature 466, 243-7, (2010). View articlePMID: 20555325

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