PF03846

Cell division inhibitor SulA

Pfam entry
Member databasePfam
Pfam typefamily
Short nameSulA
ClanP-loop_NTPase
AuthorTIGRFAMs; Griffiths-Jones SR;0000-0001-6043-807X
Sequence Ontology0100021

Description

This family includes the cell division inhibitor SulA, which binds to FtsZ and halts cell division
[1]
. It binds the T7 loop surface of FtsZ, which locates opposite the nucleotide-binding site, and blocks polymer formation
[1]
.

References

1.Crystal structure of the SOS cell division inhibitor SulA and in complex with FtsZ. Cordell SC, Robinson EJ, Lowe J. Proc. Natl. Acad. Sci. U.S.A. 100, 7889-94, (2003). View articlePMID: 12808143

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