Member database | Pfam |
Pfam type | domain |
Short name | CHASE |
Clan | Cache |
Author | Yeats C;0000-0003-0080-6242 |
Sequence Ontology | 0000417 |
Description
This domain is found in the extracellular portion of receptor-like proteins - such as serine/threonine kinases and adenylyl cyclases
[2, 1]. This is a ligand-binding domain that binds cytokinin (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
References
1.CHASE: an extracellular sensing domain common to transmembrane receptors from prokaryotes, lower eukaryotes and plants. Mougel C, Zhulin IB. Trends Biochem. Sci. 26, 582-4, (2001). View articlePMID: 11590001
2.The CHASE domain: a predicted ligand-binding module in plant cytokinin receptors and other eukaryotic and bacterial receptors. Anantharaman V, Aravind L. Trends Biochem. Sci. 26, 579-82, (2001). View articlePMID: 11590000
Integrated to
Representative structure
3t4l: Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin