Member database | Pfam |
Pfam type | family |
Short name | ARS2 |
Clan | C2H2-zf |
Author | Moxon SJ;0000-0003-4644-1816 |
Sequence Ontology | 0100021 |
Description
Arsenite is a carcinogenic compound which can act as a co-mutagen by inhibiting DNA repair. Arsenite-resistance protein 2 is thought to play a role in arsenite resistance
[1].
References
1.Expression cloning for arsenite-resistance resulted in isolation of tumor-suppressor fau cDNA: possible involvement of the ubiquitin system in arsenic carcinogenesis. Rossman TG, Wang Z. Carcinogenesis 20, 311-6, (1999). View articlePMID: 10069470