PF07727

Reverse transcriptase (RNA-dependent DNA polymerase)

Pfam entry
Member databasePfam
Pfam typefamily
Short nameRVT_2
ClanRdRP
Author Studholme DJ;0000-0002-3010-6637 Eddy SR;0000-0001-6676-4706
Sequence Ontology0100021

Description

A reverse transcriptase gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. Reverse transcriptases occur in a variety of mobile elements, including retrotransposons, retroviruses, group II introns, bacterial msDNAs, hepadnaviruses, and caulimoviruses. This Pfam entry includes reverse transcriptases not recognised by the Pfam:PF00078 model.

References

1. Origin and evolution of retroelements based upon their reverse transcriptase sequences. Xiong Y, Eickbush TH. EMBO J. 9, 3353-62, (1990). View articlePMID: 1698615

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