PF09271

LAG1, DNA binding

Pfam entry
Member databasePfam
Pfam typedomain
Short nameLAG1-DNAbind
ClanP53-like
Author Sammut SJ;0000-0003-4472-904X
Sequence Ontology0000417

Description

Members of this family are found in various eukaryotic hypothetical proteins and in the DNA-binding protein LAG-1. They adopt a beta sandwich structure, with nine strands in two beta-sheets, in a Greek-key topology, and allow for DNA binding
[1]
. This domain is also known as RHR-N (Rel-homology region) as it related to Rel domain proteins.

References

1.Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA. Kovall RA, Hendrickson WA. EMBO J. 23, 3441-51, (2004). View articlePMID: 15297877

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