PF10513

Enhancer of polycomb-like

Pfam entry
Member databasePfam
Pfam typefamily
Short nameEPL1
Author Mistry J;0000-0003-2479-5322 Wood V;0000-0001-6330-7526
Sequence Ontology0100021

Description

This is a family of EPL1 (Enhancer of polycomb-like) proteins. The EPL1 protein is a member of a histone acetyltransferase complex which is involved in transcriptional activation of selected genes
[1]
.

References

1.The Saccharomyces cerevisiae Piccolo NuA4 histone acetyltransferase complex requires the Enhancer of Polycomb A domain and chromodomain to acetylate nucleosomes. Selleck W, Fortin I, Sermwittayawong D, Cote J, Tan S. Mol. Cell. Biol. 25, 5535-42, (2005). View articlePMID: 15964809

Further reading

2. The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals. Stankunas K, Berger J, Ruse C, Sinclair DA, Randazzo F, Brock HW. Development 125, 4055-66, (1998). View articlePMID: 9735366

3. The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres. Zhang H, Richardson DO, Roberts DN, Utley R, Erdjument-Bromage H, Tempst P, Cote J, Cairns BR. Mol. Cell. Biol. 24, 9424-36, (2004). View articlePMID: 15485911

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