Member database | Pfam |
Pfam type | family |
Short name | Methyltrans_SAM |
Clan | NADP_Rossmann |
Author | Coggill P;0000-0001-5731-1588 |
Sequence Ontology | 0100021 |
Description
Members of this family are S-adenosylmethionine-dependent methyltransferases from gamma-proteobacterial species. The diversity in the roles of methylation is matched by the almost bewildering number of methyltransferase enzymes that catalyse the methylation reaction. Although several classes of methyltransferase enzymes are known, the great majority of methylation reactions are catalysed by the S-adenosylmethionine-dependent methyltransferases.
References
1. SAM (dependent) I AM: the S-adenosylmethionine-dependent methyltransferase fold. Martin JL, McMillan FM. Curr. Opin. Struct. Biol. 12, 783-93, (2002). View articlePMID: 12504684
Integrated to
Representative structure
3c0k: Crystal Structure of a ribosomal RNA methyltranferase