Member database | Pfam |
Pfam type | domain |
Short name | RAG2_PHD |
Clan | RING |
Author | Bateman A;0000-0002-6982-4660 |
Sequence Ontology | 0000417 |
Description
This domain is found at the C-terminus of the RAG2 protein. The structure of this domain has been shown bound to histone H3 trimethylated at lysine 4 (H3K4me3)
[1].
References
1.RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Matthews AG, Kuo AJ, Ramon-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA. Nature 450, 1106-10, (2007). View articlePMID: 18033247
Integrated to
Representative structure
2v89: Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide at 1.1A resolution