PF13401

AAA domain

Pfam entry
Member databasePfam
Pfam typedomain
Short nameAAA_22
ClanP-loop_NTPase
Author Bateman A;0000-0002-6982-4660
Sequence Ontology0000417

Description
Imported from IPR049945

This entry represents a number of closely related AAA+ ATPase domains from proteins involved in diverse processes such as DNA replication, DNA transposition and mRNA splicing. Amongst the proteins containing this domain are Origin recognition complex (ORC) subunits
[2]
, Transposon Tn7 transposition protein TnsC
[4]
, cell division control proteins
[1, 5]
and pre-mRNA-splicing factor ATP-dependent RNA helicases
[3]
.

References
Imported from IPR049945

1.Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear division. Bueno A, Russell P. EMBO J. 11, 2167-76, (1992). PMID: 1600944

2.Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6. Schmidt JM, Bleichert F. Nat Commun 11, 4263, (2020). PMID: 32848132

3.Genome-wide comparative in silico analysis of the RNA helicase gene family in Zea mays and Glycine max: a comparison with Arabidopsis and Oryza sativa. Xu R, Zhang S, Huang J, Zheng C. PLoS One 8, e78982, (2013). PMID: 24265739

4.Structural basis for DNA targeting by the Tn7 transposon. Shen Y, Gomez-Blanco J, Petassi MT, Peters JE, Ortega J, Guarne A. Nat Struct Mol Biol 29, 143-151, (2022). View articlePMID: 35173349

5.ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae. Santocanale C, Diffley JF. EMBO J 15, 6671-9, (1996). PMID: 8978693

Wikipedia

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.