PF17913

FHA domain

Pfam entry
Member databasePfam
Pfam typedomain
Short nameFHA_2
ClanSMAD-FHA
Author Bateman A;0000-0002-6982-4660
Sequence Ontology0000417

Description

This entry represents a divergent FHA domain which in PNK binds to phosphorylated segment of XRCC1
[1]
.

References

1.Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK. Ali AA, Jukes RM, Pearl LH, Oliver AW. Nucleic Acids Res. 37, 1701-12, (2009). View articlePMID: 19155274

Further reading

2. CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response. Becherel OJ, Jakob B, Cherry AL, Gueven N, Fusser M, Kijas AW, Peng C, Katyal S, McKinnon PJ, Chen J, Epe B, Smerdon SJ, Taucher-Scholz G, Lavin MF. Nucleic Acids Res. 38, 1489-503, (2010). View articlePMID: 20008512

3. The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase. Bernstein NK, Williams RS, Rakovszky ML, Cui D, Green R, Karimi-Busheri F, Mani RS, Galicia S, Koch CA, Cass CE, Durocher D, Weinfeld M, Glover JN. Mol. Cell 17, 657-70, (2005). View articlePMID: 15749016

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