Member database | Pfam |
Pfam type | domain |
Short name | HisK-N-like |
Clan | Globin |
Author | Aravind L;0000-0003-0771-253X Iyer LM;0000-0002-4844-2022 Chuguransky S;0000-0002-0520-0736 |
Sequence Ontology | 0000417 |
Description
Predicted non-heme-binding version of the Globin domain identified in ASK signalosome. Displays strongest affinities to the HisK-N family of sensor domains, which inhibit histidine kinase activation required for sporulation in bacteria of the firmicutes lineage. This globin domain is predicted to represent an independent sensory element recognizing a fatty acid or a related membrane-derived molecule which regulates activity of the ASK signalosome in apoptosis
[1].