. These are PLP-dependent decarboxylases that catalyse tyrosine decarboxylation to produce tyramine. This domain may play a regulatory role.
References
1.Monoamine Biosynthesis via a Noncanonical Calcium-Activatable Aromatic Amino Acid Decarboxylase in Psilocybin Mushroom. Torrens-Spence MP, Liu CT, Pluskal T, Chung YK, Weng JK. ACS Chem Biol 13, 3343-3353, (2018). PMID: 30484626
2.Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding. Zhu H, Xu G, Zhang K, Kong X, Han R, Zhou J, Ni Y. Sci Rep 6, 27779, (2016). PMID: 27292129
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.