Member database | Pfam |
Pfam type | domain |
Short name | Gp6_C-III |
Author | Bateman A;0000-0002-6982-4660 Lazaro Pinto Beatriz;0000-0001-6837-2941 |
Sequence Ontology | 0000417 |
Description
Baseplate structural protein gp6 is located next to the tail tube and is an intermediate (or inner) baseplate protein involved in tail assembly. Two molecules of gp6 form a complex with gp25 and gp7 which is involved sheath contraction [1-3]. This domain has been described as C-terminal domain III.
References
1. The structure of gene product 6 of bacteriophage T4, the hinge-pin of the baseplate. Aksyuk AA, Leiman PG, Shneider MM, Mesyanzhinov VV, Rossmann MG. Structure 17, 800-8, (2009). View articlePMID: 19523898
2. Role of bacteriophage T4 baseplate in regulating assembly and infection. Yap ML, Klose T, Arisaka F, Speir JA, Veesler D, Fokine A, Rossmann MG. Proc Natl Acad Sci U S A 113, 2654-9, (2016). PMID: 26929357
3. Structure of the T4 baseplate and its function in triggering sheath contraction. Taylor NM, Prokhorov NS, Guerrero-Ferreira RC, Shneider MM, Browning C, Goldie KN, Stahlberg H, Leiman PG. Nature 533, 346-52, (2016). View articlePMID: 27193680