PF22019

alpha-1,4-glucan branching enzyme GlgB, N-terminal domain

Pfam entry
Member databasePfam
Pfam typedomain
Short nameGlgB_N
ClanGHD
Author Bateman A;0000-0002-6982-4660 Andreeva A;0000-0002-0450-0091
Sequence Ontology0000417

Description

This is the N-terminal beta-sandwich domain of alpha-1,4-glucan branching enzyme GlgB and related proteins. This domain has a differential preference in substrate recognition and binding during amylase activity, when amylose is used as a substrate
[1]
.

References

1.Crystal structure of full-length Mycobacterium tuberculosis H37Rv glycogen branching enzyme: insights of N-terminal beta-sandwich in substrate specificity and enzymatic activity. Pal K, Kumar S, Sharma S, Garg SK, Alam MS, Xu HE, Agrawal P, Swaminathan K. J Biol Chem 285, 20897-903, (2010). View articlePMID: 20444687

Further reading

2. Crystal Structures of Escherichia coli Branching Enzyme in Complex with Linear Oligosaccharides. Feng L, Fawaz R, Hovde S, Gilbert L, Chiou J, Geiger JH. Biochemistry 54, 6207-18, (2015). View articlePMID: 26280198

3. Crystal structures of Escherichia coli branching enzyme in complex with cyclodextrins. Feng L, Fawaz R, Hovde S, Sheng F, Nosrati M, Geiger JH. Acta Crystallogr D Struct Biol 72, 641-7, (2016). View articlePMID: 27139627

4. Bound Substrate in the Structure of Cyanobacterial Branching Enzyme Supports a New Mechanistic Model. Hayashi M, Suzuki R, Colleoni C, Ball SG, Fujita N, Suzuki E. J Biol Chem 292, 5465-5475, (2017). View articlePMID: 28193843

5. The X-ray crystallographic structure of Escherichia coli branching enzyme. Abad MC, Binderup K, Rios-Steiner J, Arni RK, Preiss J, Geiger JH. J. Biol. Chem. 277, 42164-70, (2002). View articlePMID: 12196524

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.