PF22421

Tyrosine--tRNA ligase SYY-like C-terminal domain

Pfam entry
Member databasePfam
Pfam typedomain
Short nameSYY_C-terminal
ClanS4
Author Bateman A;0000-0002-6982-4660 Chuguransky S;0000-0002-0520-0736
Sequence Ontology0000417

Description

This entry represents the C-terminal domain of Tyrosine--tRNA ligases which contains the S4 motif that binds RNA [1-5].

References

1. Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution. Schluenzen F, Tocilj A, Zarivach R, Harms J, Gluehmann M, Janell D, Bashan A, Bartels H, Agmon I, Franceschi F, Yonath A. Cell 102, 615-23, (2000). View articlePMID: 11007480

2. Structure and dynamics of the anticodon arm binding domain of Bacillus stearothermophilus Tyrosyl-tRNA synthetase. Guijarro JI, Pintar A, Prochnicka-Chalufour A, Guez V, Gilquin B, Bedouelle H, Delepierre M. Structure 10, 311-7, (2002). View articlePMID: 12005430

3. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Carter AP, Clemons WM, Brodersen DE, Morgan-Warren RJ, Wimberly BT, Ramakrishnan V. Nature 407, 340-8, (2000). View articlePMID: 11014183

4. Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3. Pioletti M, Schlunzen F, Harms J, Zarivach R, Gluhmann M, Avila H, Bashan A, Bartels H, Auerbach T, Jacobi C, Hartsch T, Yonath A, Franceschi F. EMBO J. 20, 1829-39, (2001). View articlePMID: 11296217

5. Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors. Qiu X, Janson CA, Smith WW, Green SM, McDevitt P, Johanson K, Carter P, Hibbs M, Lewis C, Chalker A, Fosberry A, Lalonde J, Berge J, Brown P, Houge-Frydrych CS, Jarvest RL. Protein Sci. 10, 2008-16, (2001). View articlePMID: 11567092

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