PF22513

Antitoxin FitA-like, ribbon-helix-helix

Pfam entry
Member databasePfam
Pfam typedomain
Short nameFitA-like_RHH
ClanMet_repress
Author Bateman A;0000-0002-6982-4660 Lazaro Pinto Beatriz;0000-0001-6837-2941
Sequence Ontology0000417

Description

This domain is found in Antitoxin FitA from Neisseria gonorrhoeae and similar bacterial sequences. FitA is the antitoxin component of a type II toxin-antitoxin (TA) system. It binds DNA through its ribbon-helix-helix motif (this entry)
[1]
.

References

1.Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. Mattison K, Wilbur JS, So M, Brennan RG. J. Biol. Chem. 281, 37942-51, (2006). View articlePMID: 16982615

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