Member database | Pfam |
Pfam type | domain |
Short name | FitA-like_RHH |
Clan | Met_repress |
Author | Bateman A;0000-0002-6982-4660 Lazaro Pinto Beatriz;0000-0001-6837-2941 |
Sequence Ontology | 0000417 |
Description
This domain is found in Antitoxin FitA from Neisseria gonorrhoeae and similar bacterial sequences. FitA is the antitoxin component of a type II toxin-antitoxin (TA) system. It binds DNA through its ribbon-helix-helix motif (this entry)
[1].
References
1.Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. Mattison K, Wilbur JS, So M, Brennan RG. J. Biol. Chem. 281, 37942-51, (2006). View articlePMID: 16982615