Member database | Pfam |
Pfam type | domain |
Short name | C1-like_CT |
Clan | RING |
Author | Bateman A;0000-0002-6982-4660 Sanchez-Pulido L;0000-0002-2300-8502 |
Sequence Ontology | 0000417 |
Description
This entry includes variations of the protein kinase C1 domain that is characterised by a rich cysteine content. This domain is involved in binding many ligands, which include diacylglycerol, phorbol esters and zinc
[1].
References
1.Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Katti SS, Krieger IV, Ann J, Lee J, Sacchettini JC, Igumenova TI. Nat Commun 13, 2695, (2022). View articlePMID: 35577811