PF23282

Disease resistance protein Roq1-like, winged-helix domain

Pfam entry
Member databasePfam
Pfam typedomain
Short nameWHD_ROQ1
ClanHTH
Author Bateman A;0000-0002-6982-4660 Lazaro Pinto Beatriz;0000-0001-6837-2941
Sequence Ontology0000417

Description

This is the winged-helix domain (WHD) of Disease resistance protein Roq1 from Nicotiana benthamiana, which specifically recognises the Xanthomonas and Pseudomonas effector proteins XopQ and HopQ1, and triggers cell death. Members of this family are found in plants.

References

1. Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ. Martin R, Qi T, Zhang H, Liu F, King M, Toth C, Nogales E, Staskawicz BJ. Science 370, (2020). PMID: 33273074

2. Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme. Ma S, Lapin D, Liu L, Sun Y, Song W, Zhang X, Logemann E, Yu D, Wang J, Jirschitzka J, Han Z, Schulze-Lefert P, Parker JE, Chai J. Science 370, (2020). PMID: 33273071

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