Member database | PROSITE patterns |
PROSITE patterns type | conserved site |
Short name | CUTINASE_1 |
Description
Cutinase [1] is an extracellular fungal enzyme that catalyzes the hydrolysis
of cutin, an insoluble lipid-polyester that forms the structure of plant
cuticle. Cutinase allows pathogenic fungi to penetrate through the host plant
cuticular barrier during the initial stage of fungal infection. Cutinase is a
serine esterase which contains the classical catalytic triad (Asp, Ser, and
His) found in the serine hydrolases
[1].
Two cutinase-like proteins (MtCY39.35 and MtCY339.08c) have been found in the
genome of the bacteria Mycobacterium tuberculosis.
The sequence around the catalytic residues is well conserved in the sequence
of the known fungal cutinases and can be used as signature patterns.
References
1.Fusarium solani cutinase is a lipolytic enzyme with a catalytic serine accessible to solvent. Martinez C, De Geus P, Lauwereys M, Matthyssens G, Cambillau C. Nature 356, 615-8, (1992). View articlePMID: 1560844