Member database | PROSITE patterns |
PROSITE patterns type | conserved site |
Short name | APP_CUBD |
Description
References
1.Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein. Dahms SO, Hoefgen S, Roeser D, Schlott B, Guhrs KH, Than ME. Proc Natl Acad Sci U S A 107, 5381-6, (2010). PMID: 20212142
2.The E2 domains of APP and APLP1 share a conserved mode of dimerization. Lee S, Xue Y, Hu J, Wang Y, Liu X, Demeler B, Ha Y. Biochemistry 50, 5453-64, (2011). View articlePMID: 21574595
3.Quantification of copper binding to amyloid precursor protein domain 2 and its Caenorhabditis elegans ortholog. Implications for biological function. Leong SL, Young TR, Barnham KJ, Wedd AG, Hinds MG, Xiao Z, Cappai R. Metallomics 6, 105-16, (2014). PMID: 24276282
4.The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain. Wang Y, Ha Y. Mol. Cell 15, 343-53, (2004). View articlePMID: 15304215
5.Structural studies of the Alzheimer's amyloid precursor protein copper-binding domain reveal how it binds copper ions. Kong GK, Adams JJ, Harris HH, Boas JF, Curtain CC, Galatis D, Masters CL, Barnham KJ, McKinstry WJ, Cappai R, Parker MW. J. Mol. Biol. 367, 148-61, (2007). View articlePMID: 17239395
6.Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis. Barnham KJ, McKinstry WJ, Multhaup G, Galatis D, Morton CJ, Curtain CC, Williamson NA, White AR, Hinds MG, Norton RS, Beyreuther K, Masters CL, Parker MW, Cappai R. J. Biol. Chem. 278, 17401-7, (2003). View articlePMID: 12611883
7.Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Rossjohn J, Cappai R, Feil SC, Henry A, McKinstry WJ, Galatis D, Hesse L, Multhaup G, Beyreuther K, Masters CL, Parker MW. Nat. Struct. Biol. 6, 327-31, (1999). View articlePMID: 10201399
8.Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization. Xue Y, Lee S, Ha Y. Proc. Natl. Acad. Sci. U.S.A. 108, 16229-34, (2011). View articlePMID: 21930949