PS00957

NAD-dependent glycerol-3-phosphate dehydrogenase signature

PROSITE patterns entry
Member databasePROSITE patterns
PROSITE patterns typeconserved site
Short nameNAD_G3PDH

Description

NAD-dependent glycerol-3-phosphate dehydrogenase (EC 1.1.1.8) (GPD) catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3- phosphate. It is a eukaryotic cytosolic homodimeric protein of about 40 Kd. As a signature pattern we selected a glycine-rich region that is probably
[1]
involved in NAD-binding.

References

1.Prediction of secondary structural elements in glycerol-3-phosphate dehydrogenase by comparison with other dehydrogenases. Otto J, Argos P, Rossmann MG. Eur. J. Biochem. 109, 325-30, (1980). View articlePMID: 6773774

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