Member database | PROSITE patterns |
PROSITE patterns type | conserved site |
Short name | ISPD |
Description
The bacterial ispD protein
[1] catalyzes the third step of the deoxyxylulose-
5-phosphate pathway (DXP) of isoprenoid biosynthesis; the formation of 4-
diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol
4-phosphate.
These proteins can be picked up in the database by a pattern centered on a
central conserved region that contains a conserved Asp and Arg residues.
References
1.Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol. Rohdich F, Wungsintaweekul J, Fellermeier M, Sagner S, Herz S, Kis K, Eisenreich W, Bacher A, Zenk MH. Proc. Natl. Acad. Sci. U.S.A. 96, 11758-63, (1999). View articlePMID: 10518523