Member database | SUPERFAMILY |
SUPERFAMILY type | homologous superfamily |
Description Imported from IPR035513
This superfamily represents pectin methylesterases (PMEs) and invertases complex, and the uncharacterised protein Os08g from Oryza sativa subsp. japonica (Rice).
This domain inhibits pectin methylesterases (PMEs) and invertases through formation of a non-covalent 1:1 complex
[2]. It has been implicated in the regulation of fruit development, carbohydrate metabolism and cell wall extension
[1]. It may also be involved in inhibiting microbial pathogen PMEs. It has been observed that it is often expressed as a large inactive preprotein
[2]. It is also found at the N-termini of PMEs, suggesting that both PMEs and their inhibitor are expressed as a single polyprotein and subsequently processed. It has two disulphide bridges and is mainly α-helical
[1].
References Imported from IPR035513
1.Kiwi protein inhibitor of pectin methylesterase amino-acid sequence and structural importance of two disulfide bridges. Camardella L, Carratore V, Ciardiello MA, Servillo L, Balestrieri C, Giovane A. Eur. J. Biochem. 267, 4561-5, (2000). View articlePMID: 10880981
2.A glycoprotein inhibitor of pectin methylesterase in kiwi fruit. Purification by affinity chromatography and evidence of a ripening-related precursor. Giovane A, Balestrieri C, Quagliuolo L, Castaldo D, Servillo L. Eur. J. Biochem. 233, 926-9, (1995). View articlePMID: 8521860
Integrated to
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Representative structure
2cj4: Crystal Structure of a Cell Wall Invertase Inhibitor from Tobacco at pH 4.6