Member database | SUPERFAMILY |
SUPERFAMILY type | homologous superfamily |
Description Imported from IPR035914
* Mammalian complement subcomponents C1s/C1r, which form the calcium-dependent complex C1, the first component of the classical pathway of the complement system.
* Cricetidae sp. (Hamster) serine protease Casp, which degrades type I and IV collagen and fibronectin in the presence of calcium.
* Mammalian complement-activating component of Ra-reactive factor (RARF), a protease that cleaves the C4 component of complement.
* Vertebrate enteropeptidase (
* Vertebrate bone morphogenic protein 1 (BMP-1), a protein which induces cartilage and bone formation and expresses metalloendopeptidase activity.
* Sea urchin blastula proteins BP10 and SpAN.
* Caenorhabditis elegans hypothetical proteins F42A10.8 and R151.5.
* Neuropilin (A5 antigen), a calcium-independent cell adhesion molecule that functions during the formation of certain neuronal circuits.
* Fibropellins I and III from Strongylocentrotus purpuratus (Purple sea urchin).
* Mammalian hyaluronate-binding protein TSG-6 (or PS4), a serum and growth factor induced protein.
* Mammalian spermadhesins.
* Xenopus laevis embryonic protein UVS.2, which is expressed during dorsoanterior development.
References Imported from IPR035914
1.Expression of the CUB domain containing protein 1 (CDCP1) gene in colorectal tumour cells. Perry SE, Robinson P, Melcher A, Quirke P, Buhring HJ, Cook GP, Blair GE. FEBS Lett. 581, 1137-42, (2007). View articlePMID: 17335815
2.The CUB domain. A widespread module in developmentally regulated proteins. Bork P, Beckmann G. J. Mol. Biol. 231, 539-45, (1993). View articlePMID: 8510165
3.Insights into how CUB domains can exert specific functions while sharing a common fold: conserved and specific features of the CUB1 domain contribute to the molecular basis of procollagen C-proteinase enhancer-1 activity. Blanc G, Font B, Eichenberger D, Moreau C, Ricard-Blum S, Hulmes DJ, Moali C. J. Biol. Chem. 282, 16924-33, (2007). View articlePMID: 17446170
4.Complement components C1r/C1s, bone morphogenic protein 1 and Xenopus laevis developmentally regulated protein UVS.2 share common repeats. Bork P. FEBS Lett. 282, 9-12, (1991). View articlePMID: 2026272