SSF75005

Arabinanase/levansucrase/invertase

SUPERFAMILY entry
Member databaseSUPERFAMILY
SUPERFAMILY typehomologous superfamily

Description
Imported from IPR023296

This is a five-bladed β-propeller fold catalytic domain where each blade has four twisted antiparallel β-strands radially orientated around a pseudo-5-fold axis
[5]
. It can be found in the glycosyl hydrolase family 43 (GH43) members, including beta-xylosidases, alpha-L-arabinanases and bifunctional beta-xylosidases/alpha-L-arabinofuranosidases
[1, 2, 3]
. This domain can also be found in other GH families, such as GH32, GH62 and GH68
[4]
.

References
Imported from IPR023296

1.Crystal structure of an inverting GH43 1,5-alpha-L-arabinanase from Geobacillus stearothermophilus complexed with its substrate. Alhasid A, Ben-David A, Tabachnikov O, Wolf D, Naveh E, Zolotnitsky G, Shoham Y, Shoham G. Biochem. J. (2009). PMID: 19505290

2.Structural framework of fructosyl transfer in Bacillus subtilis levansucrase. Meng G, Futterer K. Nat. Struct. Biol. 10, 935-41, (2003). View articlePMID: 14517548

3.The three-dimensional structure of invertase (beta-fructosidase) from Thermotoga maritima reveals a bimodular arrangement and an evolutionary relationship between retaining and inverting glycosidases. Alberto F, Bignon C, Sulzenbacher G, Henrissat B, Czjzek M. J. Biol. Chem. 279, 18903-10, (2004). View articlePMID: 14973124

4.Structural analysis of a glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase in complex with xylotetraose reveals a different binding mechanism compared with other members of the same family. Vandermarliere E, Bourgois TM, Winn MD, van Campenhout S, Volckaert G, Delcour JA, Strelkov SV, Rabijns A, Courtin CM. Biochem. J. 418, 39-47, (2009). View articlePMID: 18980579

5.GH62 arabinofuranosidases: Structure, function and applications. Wilkens C, Andersen S, Dumon C, Berrin JG, Svensson B. Biotechnol. Adv. 35, 792-804, (2017). View articlePMID: 28669588

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