GenProp0251 - ClpXP degradation machine

Type: SYSTEM

Author: Haft DH

Description

This property describes an energy-dependent protease, one of whose tasks is degradation of abortively translated proteins tagged by the tmRNA trans-translation system. ClpX is an ATPase that unfolds target proteins for degradation; ClpP is a protease in complex with ClpX. SspB is an example of an adaptor that brings targets, including but not restricted to proteins tagged by trans-translation, to the ClpXP machine.

References

    None

Database Links

    None

Steps

StepEvidenceGo Terms
1. Adaptor SspB
Optional
IPR007481 - None
2. Temp clpA
Optional
IPR013461 - TIGR02639None
3. Clp protease proteolytic subunit ClpPIPR001907 - TIGR00493None
4. Temp clpS
Optional
IPR003769 - None
5. Clp protease ATP-binding subunit ClpXIPR004487 - TIGR00382None
Threshold: 0