A0A167V0D5
Genome polyprotein
UniProtKB/TrEMBL protein
Short name | A0A167V0D5_ZIKV |
Length | 3423 amino acids |
Species | Zika virus (ZIKV) |
Gene | GP1 |
Function | Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter |
Family membership |
Entry matches to this protein
Representative families
Representative domains
Low pH trimer interface
Homodimer interface
Low pH domain interface
Glycoprotein E binding interface
ATP binding site
Homodimer interface
Putative ATP binding site
SAM binding site
Active site
Nucleic acid substrate binding site
METAL: Zinc 1.
METAL: Zinc 2.
METAL: Zinc 2; via tele nitrogen.
METAL: Zinc 1; via tele nitrogen.
DISULFID:
BINDING: S-adenosyl-L-methionine; via carbonyl oxygen.
BINDING: S-adenosyl-L-methionine.
ACT_SITE: Charge relay system; for serine protease NS3 activity.
phobius: NON_CYTOPLASMIC_DOMAIN
phobius: TRANSMEMBRANE
phobius: CYTOPLASMIC_DOMAIN
tmhmm: TMhelix
InterPro GO terms
biological process
molecular function
- protein dimerization activity (GO:0046983)
- serine-type endopeptidase activity (GO:0004252)
- RNA binding (GO:0003723)
- RNA helicase activity (GO:0003724)
- ATP binding (GO:0005524)
- helicase activity (GO:0004386)
- mRNA 5'-cap (guanine-N7-)-methyltransferase activity (GO:0004482)
- mRNA (nucleoside-2'-O-)-methyltransferase activity (GO:0004483)
- RNA-dependent RNA polymerase activity (GO:0003968)
- hydrolase activity, acting on acid anhydrides (GO:0016817)
- ribonucleoside triphosphate phosphatase activity (GO:0017111)
- structural molecule activity (GO:0005198)
- double-stranded RNA binding (GO:0003725)
- methyltransferase activity (GO:0008168)
cellular component