A0A1A2P466
Inosine-5'-monophosphate dehydrogenase
UniProtKB/TrEMBL protein
Short name | A0A1A2P466_9MYCO |
Length | 536 amino acids |
Species | Mycobacterium sp. E1319 |
Gene | guaB |
Function | Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growt... |
Family membership |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative families
Representative domains
Active site
Ligand binding site I
Ligand binding site II
ACT_SITE: Proton acceptor.
ACT_SITE: Thioimidate intermediate.
NP_BIND: NAD.
METAL: Potassium; via carbonyl oxygen.
BINDING: IMP.
REGION: IMP binding.
PIRSR
ACT_SITE: Thioimidate intermediate.
METAL: Potassium; via carbonyl oxygen.
InterPro GO terms
biological process
molecular function
cellular component
- None
Panther GO terms
PTHR11911:SF111
biological process
molecular function
cellular component