A0A219Y1I2

Genome polyprotein

UniProtKB/TrEMBL protein
Short nameA0A219Y1I2_HED68
Length2187 amino acids
SpeciesHuman enterovirus D68 (EV68)
Function
Acts as a primer for viral RNA replication and remains covalently bound to viral genomic RNA. VPg is uridylylated prior to priming replication into VPg-pUpU. The oriI viral genomic sequence may act as a template for this. The VPg-pUpU is then used as...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
121872004006008001,0001,2001,4001,6001,8002,000
10002000
PCV_3…SF3_…Rhv_5Pic…RhvRhvEnterovirus_RdRp
Representative domains
rhv_likerhv_li…rhv_like
Drug-binding pocket
Enterovirus_RdRp
RNA binding site
Conserved polymerase motif F
Conserved polymerase motif B
Conserved polymerase motif A
NTP binding site
Conserved polymerase motif C
PIRSR
ACT_SITE: For RdRp activity.
NP_BIND: ATP.
SITE: Cleavage; by protease 3C.

InterPro GO terms

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